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Platform research

A promising foundation for frequency wellness.

Laboratory and early human studies have demonstrated precise biological signal responses, practical use, and an encouraging early safety profile. Together, they inform a distinct non ingestible platform for future companion wellness research.

What the platform research shows

Precision, practicality, and a positive path forward.

Each study explores a different part of the platform. Together, they offer useful direction for the future of frequency informed companion routines.

01

Precision

Preclinical work showed targeted, measurable biological signal responses.

02

Practical use

Early human studies demonstrated that the platform could be used in real world settings.

03

Early safety

Prospective platform research reported an encouraging safety profile in the protocols studied.

Explore the research

Read the studies shaping the platform.

Every finding links directly to its original source, so families can explore the science for themselves.

Direct platform · Preclinical 2017

Precision knockdown of EGFR using recorded radiofrequency energy

Design

Cell assays plus an orthotopic xenograft model

What it found. Exposure to an EGFR-siRNA RFE signal reduced EGFR mRNA by 30–70% and protein by about 60% versus controls, with pathway specificity checks.

“An RFE signal can induce a specific siRNA-like effect on cells.”
Read the source
Direct platform · Human 2019

Voyager ulRFE feasibility study in recurrent glioblastoma

Design

Open-label, two-arm feasibility study

What it found. The study reported median overall survival of 8.04 and 6.89 months across two signal arms and found the device feasible to use.

“No serious adverse events associated with Voyager were reported.”
Read the source
Direct platform · Human 2023

Expanded Voyager safety and feasibility study

Design

Prospective, open-label, multicenter study

What it found. Device-related adverse events were uncommon and no device-related serious adverse events were reported.

Read the source
Direct platform · Preclinical 2022

Defined frequency signals reduced pain responses across validated models

Design

Controlled testing by a specialist third party research organization

What it found. A subset of low and ultra low frequency signals produced statistically significant reductions in pain related responses across visceral, neuropathic, and inflammatory models. Frequency refinement further strengthened the reported effects.

Read the source

How research grows

From a measured signal to more companion moments.

01

Discover

Identify and record meaningful signal patterns through laboratory research.

02

Demonstrate

Study precise responses, practical use, and safety through focused platform research.

03

Explore

Bring that learning into real companion routines, with thoughtful research and owner experience.

The next chapter

Frequency wellness is ready for more companion moments.

The platform studies provide a positive foundation for the next phase: careful companion research around settling, rest, connection, and everyday wellbeing.

Explore companion research
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